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Transfusional Medicine

10
Publications
50.00
%Q1
8
Number of citations
62.50
% Open Access Publications
9
Ongoing Projects
0
Number of Presented Theses
0
Number of Active Clinical Trials
Transfusion medicine encompasses various care and research lines around immunohematology, cellular immunotherapy, congenital coagulopathies and regenerative medicine. A. Obtaining red blood cells generated in vitro to enhance the panel of blood donors with minority blood groups. N Nogues group has established a technology for immortalization of red blood cell lines to improve panels. B. Technological improvements for diagnosis of hereditary haemorrhagic diseases. F Vidal group has developed and validated new NGS technologies in the study of these disorders. C. Creation of a bank of T cells. S Querol group is developing strategies for generation and ex vivo production of T lymphocytes to treat infectious and oncohematological diseases. D. Blood safety. S Sauleda group is conducting epidemiological surveillance on emerging and re-emerging transfusion-transmitted infectious diseases and is developing immunological and molecular tools to better understand their physiopathology.

eCORE

  • Advanced Therapies and Advanced Interventions, Nanomedicine, Transplant & Donation

Team

Group Leader
Rafael Parra López

Principal Investigator (PI)
Francisco Vidal Perez, Nuria Nogues Galvez, Sergi Querol Giner

Researchers
Sofia Alonso Mateos, Gemma Aran Canals, Carmen Azqueta Molluna, Marta Bes Maijo, Nina Borràs Agustí, Laia Closa Gil, Margarita Codinach Creus, Irene Corrales Insa, Joaquim Delgadillo Duarte, Emma Enrich Rande, Rubén Escribá Piera, Elisenda Farssac Busquets, Jesus Fernandez Sojo, Iris Garcia Martínez, Cecilia González Santesteban, Maria Jose Herrero Mata, Carlos Hobeich Naya, Sergio Huertas Torres, Mónica Linares Alberich, Laura Martin Fernandez, Lluis Martorell Cedres, Laia Miquel Serra, Rut Mora Buch, Sara Morini, Helena Pasamar Garijo, Maria Madeleine Piron, Vanesa Pleguezuelos Hernandez, Cristina Prat Vidal, Marina Rierola Carrera, Luciano Rodríguez Gómez, Francesc Rudilla Salvador, Dinara Samarkanova, Silvia Sauleda Oliveras, Gloria Soria Guerrero

PhD Students
Verónica Pons Escoll, Sílvia Torrents Zapata, Elena Valdivia Garcia

Lab Technicians
Natàlia Comes Fernández, Carina Lera Asensio, Lorena Ramirez Orihuela, Angie Rico Blazquez

Nursing and Technical Staff
Merce Albert Bayo, Isabel Amaya Aguilar, Neus Boto Ruiz, Maria Cristina Caparros Felipe, Carles Caro Pauon, Maria Teresa Contijoch Mateos, Núria Font Cotet, Raquel Gil Muro, Marta Guerrero Parés, Fran Martinez Paneque, Carmen Montanero Gallardo, Enric Pàmies Barcons, Juan Manuel Porras Paradas, Maria Esperanza Ribas Badia, Marc Vilches Martinez

Selected Publications

Rudilla F, Carrasco-Benso MP, Pasamar H, López-Montañés M, Andrés-Rozas M, Tomás-Marín M, Company D, Moya C, Larrea L, Guerreiro M, Barba P, Arbona C, Querol S
Development and characterization of a cell donor registry for virus-specific T cell manufacture in a blood bank
HLA 2024 Mar;103(3):e15419
DOI: 10.1111/tan.15419
IF: 6.5

Escribá R, Beksac M, Bennaceur-Griscelli A, Glover JC, Koskela S, Latsoudis H, Querol S, Alvarez-Palomo B
Current Landscape of iPSC Haplobanks
Stem Cell Rev Rep. 2024 Nov;20(8):2155-2164
DOI: 10.1007/s12015-024-10783-7
IF: 4.5

Samarkanova D, Codinach M, Aran G, Guitart M, Valdivia E, Martorell L, Azqueta C, Rodriguez-Aliberas M, Soria G, Martinez N, Alonso E, Farssac E, Madrigal A, Fernandez-Sojo J
Quality and stability studies of red blood cell concentrates from umbilical cord blood compared to their adult counterparts
BLOOD TRANSFUS 2024 Aug 2
DOI: 10.2450/BloodTransfus.761.
IF: 2.4

Closa L, Samarkanova D, Lera C, Gonzalez N, Lloret M, Codinach M, Aran G, Fernandez-Sojo J, Vidal F, Soria MG, Querol S
Development of molecular sterility assay for rapid quality release of cord blood erythrocytes units for transfusion
TRANSFUSION. 2024 Dec 8
DOI: 10.1111/trf.18084.
IF: 2.5

Bayes-Genis A, Gastelurrutia P, Monguió-Tortajada M, Cámara ML, Prat-Vidal C, Cediel G, Rodríguez-Gómez L, Teis A, Revuelta-López E, Ferrer-Curriu G, Roura S, Gálvez-Montón C, Bisbal F, Vives J, Vilarrodona A, Muñoz-Guijosa C, Querol S
Implantation of a double allogeneic human engineered tissue graft on damaged heart: insights from the PERISCOPE phase I clinical trial
EBIOMEDICINE 2024 Apr;102:105060
DOI: 10.1016/j.ebiom.2024.105060
IF: 9.7

Selected Projects

Lab-grown red cells for the transfusion management of vaso-occlusive crisis in sickle cell patients
Principal Investigator: Núria Nogués
Agency: Fundació La Caixa
Funding: 666,226 €
Period: 2023 - 2026

LAB-REDCELL: Lab-grown red cells from immortalized erythroid cell lines as an alternative source of red cells with rare phenotypes for diagnostic and therapeutic applications
Principal Investigator: Núria Nogués
Agency: AEI
Funding: 156,250 €
Period: 2023 - 2024

Development of a dual CD1a/CCR9-directed CAR-T therapy for the treatment of R/R T-cell Acute Lymphoblastic Leukemia
Principal Investigator: Sergi Querol
Agency: AEI
Funding: 281,970 €
Period: 2023 - 2023

OSCAR-iNK: Off-the-Shelf iPSC-derived next generation CAR-NK cells for solid tumor allogenic immunotherapy
Principal Investigator: Sergi Querol
Agency: AEI
Funding: 97,632 €
Period: 2022 - 2025

HEMO-GAS. Recreating the embryonic niche for hematopoietic stem cell production and derivatives in human gastruloids
Principal Investigator: Núria Nogués
Agency: AEI
Funding: 120,374 €
Period: 2021- 2024

VHIR Annual Report 2024