eCORE
- Advanced Therapies and Advanced Interventions, Nanomedicine, Transplant & Donation
- Chronic, Prevalent Diseases & Aging
Team
Group Leader
Antonio Julia Cano
Principal Investigator (PI)
Josefina Cortés, Ernesto Trallero, José Alegre, Juan José de Agustín de Oro, María López, Cristina Solé, Jesús Castro, Adrià Aterido, Jordi Lladós, Nuria Palau, Raül Tortosa
Researchers
Mireia Barceló, Alba Erra, Andrea Pluma, Ramón Sanmartín, Miriam Almirall, Mayte Serrat, Mireia López, Xabier Michelena, Alejandro Gómez, Estefanía Moreno
PhD Students
Luis Coronel, Helena Borrell, Rafael Touriño, María Pascual, Esther Espartal, Sebastián Sandoval, Judith Fernández
Lab Technicians
Edgar Núñez, Aitor Ruiz, Erica Téllez, Blanca Joseph
Nursing and Technical Staff
Montserrat Sender, Hugo Fernando Ávalos, Ana Daniela Ulloa, Carlos Jorge Alcaraz, Adriana Cabrera, Natalia Nogué, Carlos Junco, Alba Frias, Ares Sellés, Josep Masramón, Viviana Sánchez, María Royo, Edgar Núñez, Aitor Ruiz, Erica Téllez, Blanca Joseph, Marta Musté, Ana Roig, Natalia Boix, Mercè Fabregat, Elena Granell
Selected Publications
Di Matteo A, Smerilli G, Di Donato S, Liu AR, Becciolini A, Camarda F, Cazenave T, Cipolletta E, Corradini D, de Agustin JJ, Destro Castaniti GM, Di Donato E, Di Geso L, Duran E, Farisogullari B, Fornaro M, Francioso F, Giorgis P, Granel A, Hernandez-Diaz C, Horvath R, Hurnakova J, Jesus D, Karadag O, Li L, Marin J, Martire MV, Michelena X, Moscioni E, Muntean L, Piga M, Rosemffet M, Rovisco J, Sahin D, Salaffi F, Saraiva L, Scioscia C, Tamas MM, Tanimura S, Venetsanopoulou A, Ventura-Rios L, Villota O, Villota-Eraso C, Voulgari PV, Vukatana G, Zacariaz Hereter J, Marzo-Ortega H, Grassi W, Filippucci E
Power Doppler signal at the enthesis and bone erosions are the most discriminative OMERACT ultrasound lesions for SpA: results from the DEUS (Defining Enthesitis on Ultrasound in Spondyloarthritis) multicentre study.
Ann Rheum Dis. 2024 Jun 12;83(7):847-857
DOI: 10.1136/ard-2023-225443
IF: 20.30
Aterido A, Lopez-Lasanta M, Blanco F, Juan-Mas A, Garcia-Vivar ML, Erra A, Perez-Garcia C, Sanchez-Fernandez SA, Sanmarti R, Fernandez-Nebro A, Alperi-Lopez M, Tornero J, Ortiz AM, Fernandez-Cid CM, Palau N, Pan W, Byrne-Steele M, Starenki D, Weber D, Rodriguez-Nunez I, Han J, Myers RM, Marsal S, Julià A
Seven-chain adaptive immune receptor repertoire analysis in rheumatoid arthritis reveals novel features associated with disease and clinically relevant phenotypes.
Genome Biol. 2024 Mar 11;25(1):68
DOI: 10.1186/s13059-024-03210-0
IF: 10.10
Domingo JC, Battistini F, Cordobilla B, Zaragoza MC, Sanmartin-Sentanes R, Alegre-Martin J, Cambras T, Castro-Marrero J
Association of circulating biomarkers with illness severity measures differentiates myalgic encephalomyelitis/chronic fatigue syndrome and post-COVID-19 condition: a prospective pilot cohort study
J Transl Med. 2024 Apr 10;22(1):343
DOI: 10.1186/s12967-024-05148-0
IF: 6.10
Roman Ivorra JA, Trallero-Araguas E, Lopez Lasanta M, Cebrian L, Lojo L, Lopez-Muniz B, Fernandez-Melon J, Nunez B, Silva-Fernandez L, Veiga Cabello R, Ahijado P, De la Morena Barrio , Costas Torrijo N, Safont B, Ornilla E, Restrepo J, Campo A, Andreu JL, Diez E, Lopez Robles A, Bollo E, Benavent D, Vilanova D, Lujan Valdes S, Castellanos-Moreira
Prevalence and clinical characteristics of patients with rheumatoid arthritis with interstitial lung disease using unstructured healthcare data and machine learning
RMD Open. 2024 Jan 30;10(1):e003353
DOI: 10.1136/rmdopen-2023-003353
IF: 5.10
Sole C, Royo M, Sandoval S, Moline T, Gabaldon A, Cortes-Hernandez J
Precise Targeting of Autoantigen-Specific B Cells in Lupus Nephritis with Chimeric Autoantibody Receptor T Cells
Int J Mol Sci. 2024 Apr 11;25(8):4226
DOI: 10.3390/ijms25084226
IF: 4.90
Selected Projects
Unraveling the dark matter of infectious diseases, environmental and genetic factors tipping the balance towards NCDs
Principal Investigator: Antonio Julià Cano
Agency: European Commission. HORIZON-HLTH-2023-DISEASE-03-07
Funding: 218,825 €
Period: 01/01/2024 – 31/12/2028
Decision on optimal combinatorial therapies in IMIDs using systems approaches. DOCTIS
Principal Investigator: Sara Marsal Barril
Agency: European Comission H2020. H2020-SCH1-BHC-02-2019
Funding: 6,260,050 €
Period: 01/01/2020 – 31/12/2025
Artritis reumatoide: de la fase preclínica a la enfermedad activa. Caracterización de los cambios sistémicos y en el tejido sinovial en el establecimiento de la enfermedad ACPA-positiva
Principal Investigator: Co-IP: María López Lasanta
Agency: Instituto de Salud Carlos III, PI23/01372
Funding: 250,000 €
Period: 01/01/2023 - 01/01/2026
Caracterización de las células patogénicas del músculo y piel de pacientes con Dermatomiositis y Síndrome Antisintetasa y estudio de aplicabilidad traslacional.
Principal Investigator: Co-IP: Ernesto Trallero Araguas
Agency: Instituto de Salud Carlos III, PI22/00708
Funding: 135,520€
Period: 01/01/2023 - 31/12/2025
Sjögren Syndrome and Atopic Dermatitis cohorts’ generation and multi-omics characterization (SSAD project)
Principal Investigator: Sara Marsal Barril, José Luis Andreu, Josep Manuel Carrascosa
Agency: IMIDomics Inc.
Funding: 1,680,000€
Period: 26/06/2023 – 26/06/2025
Patents
METHOD TO PREDICT THE LACK OF RESPONSE TO ANTI-TNF ALPHA THERAPIES
Priority Number: PCT/EP2014/066604 (US)
Priority Date: 1/08/2014
Applicants: 66% VHIR, 33,3 % H. Clinic. Licenced: IMIDOMICS S.L. 31/05/2015
RISK LOCUS FOR PSORIATIC ARTHRITIS
Priority Number: 62/151,952 (PCT)
Priority Date: 23/04/2015
Applicants: VHIR, CLINIC, IGTP. Licenced: IMIDOMICS S.L. 31/07/2015
METHOD TO PREDICT RESPONSE TO TREATMENT WITH ANTI-TNF ALPHA AGENTS
Priority Number: EP14179452.9 (PCT)
Priority Date: 1/08/2014
Applicants: VHIR Licenced: IMIDOMICS S.L. 31/07/2015
Pronóstico de respuesta al tratamiento con anti-TNFalfa en pacientes de artritis reumatoide
Priority Number: P201330650 (PCT)
Priority Date: 3/05/2013
Applicants: VHIR Licenced: IMIDOMICS S.L. 31/07/2015
METODO IN VITRO Y KIT PARA EL PRONOSTICO O PREDICCION DE LA RESPUESTA POR PARTE DE PACIENTES CON ARTRITIS REUMATOIDE AL TRATAMIENTO CON AGENTES BLOQUEANTES DEL FACTOR TNF alfa (INFLIXIMAB)
Priority Number: P200802713 (ES)
Priority Date: 24/09/2008
Applicants: VHIR Licenced: IMIDOMICS S.L. 22/06/2010
Selected Dissemination Activities
Els esmorzars de Reumatologia Pediàtrica: "Preparant les vacances: la farmaciola del pacient de reumatologia pediàtrica” Dra. Laia Martínez. “Com mantindre’m en forma si sac un infant amb un una malaltia reumàtica”. Dr. Luis Coronel Moderadora: Dra. Mireia López “Com explicar als meus familiars i amics què és el lupus eritematós sistèmic juvenil”. Dra. Laia Martínez. “Mites i llegendes de l’alimentació per a pacients amb malalties reumàtiques a l’edat pediàtrica”. Dra. Mireia López Moderadora: Dra. Estefanía Moreno
Place: Hospital Universitari Vall d’Hebron, online
Date: 01/01/1970
Brief: Webinar for patients and families
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Què és la XUEC-AIS i com accedir-hi? Sara Marsal
Place: II Jornada en Malalties Autoimmunes Sistèmiques. Sabadell
Date: 01/01/1970
Brief: Activity aimed at professionals in the territory, patients and relatives, organized by the XUEC-AIS with the support of the Catalan Health Service, and with the endorsement of the ERN ReCONNET.
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Speed dating - Nit de la Recerca 2024
Place: CosmoCaixa. Barcelona
Date: 01/01/1970
Brief: An informal meeting where participants talk to researchers about their specialities. Activity carried out within the framework of the Nit de la Recerca 2024 by Dr. Mayte Serrat
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¿El eje cerebro-intestino y la microbiota intestinal en el origen de los síntomas del Síndrome del Intestino Irritable, la ansiedad y la depresión y la fibromialgia y el síndrome de fatiga crónica?
Place: Centre Cívic Vil·la Urània. Barcelona
Date: 01/01/1970
Brief: Round table where professionals from different specialties of the Vall d'Hebron University Hospital to discuss the relationship between irritable bowel syndrome (IBS) and the main mental disorders (anxiety and depression) and non-mental disorders, such as fibromyalgia (FM) and chronic fatigue syndrome (CFS).
The professionals that participated were Dr. Javier Santos, Dra. Carmen Alonso-Cotoner (S. Aparell digestiu), Dra. Amanda Rodríguez (S. DE Salut Mental) Dra. Míriam Almirall, Dr. José Alegre, Dr. Jesús Castro, Dr. Ramon Sanmartín (S. Reumatologia), HUVH
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Visits to IMID-Biobank by students of Cicle formatiu superior and 1st Batxillerat within the framework of ESCOLAB
Place: IMID-Biobank (VHIR). Parc Científic de Barcelona. Barcelona
Date: 01/01/1970
Brief: The aim of the activity by Raúl Tortosa and Núria Palau is to discover what a biobank is and what its role is in biomedical research, seeing how the IMID-Biobank works
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