Skip to main content

Research group on Status Epilepticus and Acute Seizures

19
Publications
52.63
%Q1
38
Number of citations
33.33
% Open Access Publications
2
Ongoing Projects
1
Number of Presented Theses
25
Number of Active Clinical Trials
Our research group has been predominantly focused on investigating biomarkers associated with the occurrence of epileptic seizures and those linked to impaired cognitive performance. In the current year, the group has secured 2 competitive grants with the aim to detect cognitive decline in recently diagnosed epilepsy (PI24/00862), and to identify new biomarkers predictive of epilepsy after an acute cerebral hemorrhage (PI24/01233). The group has also been working on other competitive projects in which new biomarkers associated with status epilepticus and the development of epilepsy after a subarachnoid hemorrhage have been identified. In 2024, the group published 18 articles in peer-reviewed journals and presented its findings at national and international congresses through 45 communications. Furthermore, our group maintains a prominent position in recruiting subjects for international clinical trials related to epilepsy, actively participating in 20 ongoing trials.

eCORE

  • Brain & Mind and Behaviour

Team

Group Leader
Estevo Santamarina Pérez

Principal Investigator (PI)
Manuel Toledo Argany, Laura Abraira del Fresno, Elena Fonseca Hernández

PhD Students
Daniel Campos Fernández, Samuel Lopez Maza, Sofía Lallana Serrano

Nursing and Technical Staff
Manuel Quintana Luque, Javier Sánchez López, Enric Bellido Castillo

Selected Publications

Fonseca E, Lallana S, Ortega G, Cano A, Sarria-Estrada S, Pareto D, Quintana M, Lorenzo-Bosquet C, López-Maza S, Gifreu A, Campos-Fernández D, Abraira L, Santamarina E, Orellana A, Montrreal L, Puerta R, Aguilera N, Ramis M, de Rojas I, Ruiz A, Tárraga L, Rovira À, Marquié M, Boada M, Toledo M
Amyloid deposition in adults with drug-resistant temporal lobe epilepsy
Epilepsia. 2024 Dec;65(12):3664-3675
DOI: 10.1111/epi.18142
IF: 6.6

Campos-Fernandez D, Rodrigo-Gisbert M, Abraira L, Quintana Luque M, Santafé M, Lallana S, Fonseca E, Toledo M, Gándara DF, Arikan F, Tomasello A, Sala Padró JX, Falip M, López-Ojeda P, Gabarrós A, Sánchez A, Santamarina E
Predictive Model for Estimating the Risk of Epilepsy After Aneurysmal Subarachnoid Hemorrhage: The RISE Score
Neurology. 2024 Apr 23;102(8):e209221
DOI: 10.1212/WNL.0000000000209221
IF: 7.7

Abraira L, López-Maza S, Quintana M, Fonseca E, Toledo M, Campos-Fernández D, Lallana S, Grau-López L, Ciurans J, Jiménez M, Becerra JL, Bustamante A, Rubiera M, Penalba A, Montaner J, Álvarez Sabin J, Santamarina E
Exploratory study of blood biomarkers in patients with post-stroke epilepsy
Eur Stroke J. 2024 Sep;9(3):763-771
DOI: 10.1177/23969873241244584
IF: 5.8

Luis Restrepo-Vera J, Sala-Padró J, Parejo-Carbonell B, Ciurans J, Becerra JL, Veciana M, Campos D, García-Morales I, Quintana M, Santamarina E
Identifying risk for status epilepticus with the ADAN scale: a prospective multicenter validation study
Emergencias. 2024 Jun;36(3):197-203
DOI: 10.55633/s3me/020.2024
IF: 5.4

Schubert KM, Bicciato G, Sinka L, Abraira L, Santamarina E, Álvarez-Sabín J, Ferreira-Atuesta C, Katan M, Scherrer N, Terziev R, Döhler N, Erdélyi-Canavese B, Felbecker A, Siebel P, Winklehner M, von Oertzen TJ, Wagner JN, Gigli GL, Nilo A, Janes F, Merlino G, Valente M, Zafra-Sierra MP, Mayor-Romero LC, Conrad J, Evers S, Lochner P, Roell F, Brigo F, Bentes C, Peralta R, Pinho E Melo T, Keezer MR, Duncan JS, Sander JW, Tettenborn B, Koepp M, Galovic M
Implications for driving based on the risk of seizures after ischaemic stroke
J Neurol Neurosurg Psychiatry. 2024 Aug 16;95(9):833-837
DOI: 10.1136/jnnp-2024-333505
IF: 8.7

Selected Projects

Estudio de biomarcadores relacionados con epilepsia en la hemorragia subaracnoidea
Principal Investigator: Laura Abraira del Fresno
Agency: Fundación E. Rodríguez Pascual
Funding: 24,990 €
Period: 2023-2024

Uso de marcadores en la detección de crisis epilépticas de mal pronóstico
Principal Investigator: Estevo Santamarina Pérez
Agency: Instituto de Salud Carlos III
Funding: 73,810 €
Period: 2020-2024

Evaluación multimodal mediante biomarcadores para la predicción y manejo personalizado de la epilepsia secundaria a subaracnoidea aneurismática
Principal Investigator: Estevo Santamarina Pérez
Agency: Fundació Institut de Recerca HUVH
Funding: 117,000 €
Period: 2023-2025

Caracterització dels mecanismes fisiopatològics i clínics de l'epilèpsia d'inici tardà i etiologia desconeguda.
Principal Investigator: Laura Abraira del Fresno
Agency: Fundació Institut de Recerca HUVH
Funding: 35,000 €
Period: 2024-2025

Selected Dissemination Activities

Jornada de l'Epilèpsia
Place: Hospital Universitari Vall d'Hebron
Date: 10/08/2024
Brief: Our group organized this activity in the Epilepsy Patient Day at Vall d'Hebron Hospital in collaboration with the 'Si jo puc, tu també #EPILEP' Foundation, where professionals from our team interacted with patients with epilepsy, family members and caregivers.
MORE INFO

VHIR Annual Report 2024