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Liver Diseases

96
Publications
75.00
%Q1
992
Number of citations
76,12
% Open Access Publications
26
Ongoing Projects
5
Number of Presented Theses
67
Number of Active Clinical Trials
The Liver Diseases group is a referent in research in the liver diseases field at national and international level. We are national leaders in clinical trials covering all the spectrum of liver diseases. Another essential feature of the group is the active contribution of our members to the most significant national and international medical societies of the liver field (Executive and Scientific Committees of AEEH, Governing Board of EASL). Additionally, we have been collaborating in international consortiums and projects funded by European institutions such as Decision, Artemis, among others.

eCORE

  • Advanced Therapies and Advanced Interventions, Nanomedicine, Transplant & Donation
  • Chronic, Prevalent Diseases & Aging

Team

Group Leader
Joan Genescà Ferrer

Principal Investigator (PI)
Maria Buti Ferret, Isabel Campos Varela, Juan Ignacio Esteban Mur, Maria Martell Pérez-Alcalde, Beatriz Mínguez Rosique, Juan Manuel Pericàs Pulido, Josep Quer Sivila, Maria Del Mar Riveiro Barciela, Macarena Simon-Talero Horga, Victor Manuel Vargas Blasco, Meritxell Ventura Cots

Researchers
Lluis Castells Fusté, Immaculada Raurell Saborit, David Tabernero Caellas, Mònica Pons Delgado, Jordi Llaneras Artigues, Adriana Palom Agusti, Mónica Higuera Urbano

PhD Students
María Bermúdez Ramos, Meritxell Llorens Revull, Joan Martínez Campreciós, Elena Vargas Accarino, Judit Vidal Gonzalez, Ares Aurora Villagrasa Vilella, César Jiménez, Maria Luisa Roade Tato, Marta Ibañez Lligoña, Maria Martínez Gómez, Ana Barreira, Cristina Marcos, Sergi Colomer Castell, Carolina Campos Martinez, Juan Carlos Ruiz Cobo, Ana Feliu, Sergio Muñoz Martínez

Lab Technicians
Damir Garcia Cehic

Nursing and Technical Staff
Susana Anton Calvo, Cristina Adame Castillo, Elena de Sena Fernández, Ester Palacio Gutierrez, Marcella Salzano, Maria Margarita Torrens Buscató, Judit Vico Romero, Laura Puente Ramo, Clara Sabiote Cartes, Claudia Ana Burillo

Selected Publications

Karlsen TH, Rutter H, Carrieri P, Zelber-Sagi S, Engebretsen E, Hutchinson S, Voigt K, Guha N, Berzigotti A, Schomerus G, Gines P, Buti M, Burra P, Manns MP, Krag A, Kleinert S
The EASL-Lancet Commission on liver health in Europe: prevention, case-finding, and early diagnosis to reduce liver-related mortality.
Lancet. 2024 Apr 20;403(10436):1522-1524.
DOI: 10.1016/S0140-6736(24)00204-6
IF: 98.40

Harrison SA, Bedossa P, Guy CD, Schattenberg JM, Loomba R, Taub R, Labriola D, Moussa SE, Neff GW, Rinella ME, Anstee QM, Abdelmalek MF, Younossi Z, Baum SJ, Francque S, Charlton MR, Newsome PN, Lanthier N, Schiefke I, Mangia A, Pericas JM, Patil R, Sanyal AJ, Noureddin M, Bansal MB, Alkhouri N, Castera L, Rudraraju M, Ratziu V, Bate J, Danta M, Gan L, George J, Haque M, Hodge A, Kontorinis N, Leung C, Roberts S, Skoien R, Sood S, Strasser S, Weltman M, Hametner-Schreil S, Hofer H, Holzl B, Ludvik B, Maieron A, Peck-Radosavljevic M, Trauner M, Decaestecker J, Francque S, Geerts A, Kindt S, Laleman W, Lanthier N, Lasser L, Moreno C, Robaeys G, Van Steenkiste C, Bajaj H, Borman M, Chandok N, El Khashab M, Fraser H, Ko H, Montano-Loza A, Patel K, Puglia M, Yoshida E, Abergel A, Bardou-Jacquet E, Boursier J, Bronowicki JP, Bureau C, Castera L, Di Martino V, Habersetzer F, Larrey D, Loustaud Ratti V, Mathurin P, Maynard-Muet M, Nguyen-Khac E, Pol S, Ratziu V, Roulot D, Serfaty L, Tran A, Varaut A, Arasteh K, Arelin K, Contzen C, Demir M, Doer ff el Y, Geier A, Ingiliz P, Lammert F, Lehretz M, Schattenberg J, Schiefke I, Schute N, Zeuzem S, Banyai T, Lesch M, Makara M, Nemes J, Nyeky T, Varga M, Varkonyi IZ, Ben-Ari Z, Braun M, Francis A, Katchman H, Lurie Y, Nimer A, Safadi R, Veitsman E, Yardeni D, Zuckerman E, Angelico M, Del Ben M, Fagiuoli S, Lampertico P, Mangia A, Marra F, Mattina A, Miele L, Peta S, Pirisi M, Raimondo G, Rizzardini G, Bruneto MR, Ladron de Guevara AL, Cisneros Garza LE, Rodriguez Chavez J, Flores Figueroa J, Castillo Barradas M, Pericas JM, Rivera-Esteban JM, Casado Martin M, Ibanez Samaniego L, Conde I, Calleja Panero JL, Torras Colell X, Diago Madrid FM, Crespo Garcia J, Turnes Vazquez J, Romero Gomez M, Garcia Retortillo M, Albilos Martinez A, Berzigotti A, Dufour JF, Magenta L, Mullhaupt B, Abales D, Alazawi W, Allison M, Anstee Q, Connell S, Dokhe P, Eyre S, Forton D, Fowell A, Foxton M, Gowda M, Iyengar S, Kyriakidou C, Ch'ng CL, Manousou P, McCorry R, Newsome P, Pembroke T, Ramjee M, Ryder S, Shankar A, Sheridan D, Sieberhagen C, Thomas H, Tsochatzis E, Abdelmalek M, Adams M, Ankoma-Sey V, Arora S, Awasty V, Bashour J, Baum S, Bhargava A, Borg B, Caldwell S, Calinescu C, Challa S, Charlton M, Christensen C, DeGrauw J, Desantis D, Dunn C, Dunn W, Fine M, Firpi-Morell R, Freilich B, Fuchs M, Gonzalez M, Gunn N, Hellstern P Jr, Hsia S, Hu ff man J, Jakiche A, James G, Jenders R, Jennings W, Kepczyk T, Khazanchi A, Knapple W, Kohli A, Kosinski J, Kowdley K, Kugelmas M, Lawitz E, Lesh K, Lucas K, Manch R, Mani R, Merkes K, Meyer R, Modi A, Moore A, Morales A, Mubarak A, Newberg J, Ortiz Lasanta G, Pagadala M, Patil R, Poulos J, Ravinuthala R, Reiss G, Reynolds M, Rinella M, Ruane P, Scot J, Sheikh A, Sheikh M, Shi ff man M, Shockey G, Streja D, Syal P, Tetri B, Therapondos G, Torres D, Troter J, Wendorf G, White A, White J, Wilson M, Younes Z
A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis.
N Engl J Med. 2024 Feb 8;390(6):497-509.
DOI: 10.1056/NEJMoa2309000
IF: 96.30

Kowdley KV, Bowlus CL, Levy C, Akarca US, Alvares-da-Silva MR, Andreone P, Arrese M, Corpechot C, Francque SM, Heneghan MA, Invernizzi P, Jones D, Kruger FC, Lawitz E, Mayo MJ, Shiffman ML, Swain MG, Valera JM, Vargas V, Vierling JM, Villamil A, Addy C, Dietrich J, Germain JM, Mazain S, Rafailovic D, Tadde B, Miller B, Shu J, Zein CO, Schattenberg JM
Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis.
N Engl J Med. 2024 Feb 29;390(9):795-805.
DOI: 10.1056/NEJMoa2306185
IF: 96.30

Pericas JM, Anstee QM, Augustin S, Bataller R, Berzigotti A, Ciudin A, Francque S, Abraldes JG, Hernandez-Gea V, Pons M, Reiberger T, Rowe IA, Rydqvist P, Schabel E, Tacke F, Tsochatzis EA, Genesca J
A roadmap for clinical trials in MASH-related compensated cirrhosis.
Nat Rev Gastroenterol Hepatol. 2024 Nov;21(11):809-823.
DOI: 10.1038/s41575-024-00955-8
IF: 46.40

Kondili LA, Lazarus JV, Jepsen P, Murray F, Schattenberg JM, Korenjak M, Craxi L, Buti M
Inequities in primary liver cancer in Europe: The state of play.
J Hepatol. 2024 Apr;80(4):645-660.
DOI: 10.1016/j.jhep.2023.12.031
IF: 26.80

Selected Projects

Caracterización de las claves fisiopatológicas y fenotipos de la enfermedad del hígado graso metabólica con ingesta moderada de alcohol para identificar nuevas terapias (ReLiveR).
Principal Investigator: Meritxell Ventura Cots, Juan Manuel Pericàs
Agency: Instituto de Salud Carlos III
Funding: 183,920 €
Period: 01/01/2023 - 31/12/2025

Aislamiento y caracterización molecular de Células Tumorales Circulantes (CTCs): potenciales biomarcadores en Carcinoma Hepatocelular
Principal Investigator: Beatriz Mínguez Rosique
Agency: Instituto de Salud Carlos III
Funding: 183,920 €
Period: 01/01/2022 - 31/12/2025

Decompensated cirrhosis: Identification of new combinatorial therapies based on system approaches- DECISION_H2020-SC1-BHC2019
Principal Investigator: Joan Genescà Ferrer
Agency: European Commission
Funding: 130,472.5 €
Period: 01/04/2020 - 30/09/2025

ARTEMIs: AcceleRating the Translation of virtual twins towards a pErsonalised Management of fatty liver patients
Principal Investigator: José Raul Herance Camacho-Juan Manuel Pericàs (WP leader)
Agency: European Commission
Funding: 724,000 €
Period: 01/01/2024 - 31/12/2027

Búsqueda de biomarcadores (inmunológicos y/o celulares) predictivos de respuesta virológica o de control de la infección en la hepatitis crónica D.
Principal Investigator: Maria Buti Ferret
Agency: Instituto de Salud Carlos III
Funding: 220,000 €
Period: 01/01/2024 - 31/12/2026

Selected Dissemination Activities

Press release on results of clinical trial of resmetirom for metabolic fatty liver disease
Place: Webpages VHIR, Vall d'Hebron Campus, CIBER, National Press, Radio, TV
Date: 01/01/1970
Brief: More than 50 impacts in different media of the news with the participation of Dr. Juan Manuel Pericàs of our group.
MORE INFO

VHIR Annual Report 2024