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General Surgery

57
Publications
73.68
%Q1
80
Number of citations
50
% Open Access Publications
18
Ongoing Projects
1
Number of Presented Theses
3
Number of Active Clinical Trials
The General Surgery Research Group fosters innovation across surgical specialties, uniting clinical practice with basic science. In 2024, each subline has actively advanced its research direction. Our work spans quality of care and the pathophysiology of surgical diseases, focusing on experimental models, robotics, and digital tools. Abdominal wall research examines hernia formation, fibroblast dysfunction, pelvic floor disorders and novel biomaterials. Thoracic studies focus on lung transplant rejection and anti-leak patch development. Colorectal and esophagogastric research investigates cancer and robotic surgery. Endocrine efforts target obesity, thyroid/adrenal disease, and post-bariatric metabolic changes. Our multidisciplinary team collaborates closely, supported by a dedicated lab with expertise in extracellular matrix biology and biomaterial integration. Together, we aim to enhance surgical outcomes and deepen the scientific understanding of the conditions we treat.

eCORE

  • Advanced Therapies and Advanced Interventions, Nanomedicine, Transplant & Donation
  • Cancer
  • Chronic, Prevalent Diseases & Aging
  • Personalized Medicine, Innovative Diagnostics, Molecular Imaging & Digital Health

Team

Group Leader
Manuel Armengol Carrasco

Principal Investigator (PI)
Alejandro Solis Peña, Clara Pañella Vilamú, Eloy Espín Basany, Marc Martí Gallostra, Maria Antonia Arbos Via, Ramón Vilallonga Puy

Researchers
Alberto Jauregui Abularach, Amaia Gantxegi Madina, Ana Maria Ciscar Bellés, Clara Pañella Vilamú, Eloy Espín Basany, Fernando Ascanio Gosling, Franco Marinello, Gianluca Pellino, Iñigo Royo Crespo, Joel Rosado Rodríguez, Jordi Sabadell García, Jose Luis Sánchez García, Laura Maria Romero Vielva, Maria Pilar Martinez Lopez, Maria Teresa Quiles Pérez, Manuel López Cano, Miquel Kraft Carre, Mireia Verdaguer Tremolosa, Nivardo Rodríguez Conde, Núria Ortega Torrecilla, Oscar González López, Sandra Castro Boix, Victor Rodrigues Gonçalves

PhD Students
Arturo Cirera de Tudela, Carlos Petrola Chacón, Claudia Cabau Talarn, Esther Gil Barrionuevo, Laura Caubet Domingo, Leire Sánchez Corujo, Maria del Pilar Montoya Urbano, Maria José Gómez Jurado, Marta Barros Segura, Meritxell Pera Ferreruela, Miriam Moratal Cloquell, Montse Adell Trapé, Sergi Sánchez Cordero

Nursing and Technical Staff
Ana Bordanova Reverter, Anastasia Culea, Maria Pilar Martinez Lopez, Yoursa El-Kasmy El Kasmi

Selected Publications

Fernandez LM, São Julião GP, Santacruz CC, Renehan AG, Cano-Valderrama O, Beets GL, Azevedo J, Lorente BF, Rancaño RS, Biondo S, Espin-Basany E, Vailati BB, Nilsson PJ, Martling A, Van De Velde CJH, Parvaiz A, Habr-Gama A, Perez RO; International Watch & Wait Database Consortium (IWWD) and the Spanish Rectal Cancer Viking Consortium (VIKINGO); International Watch & Wait Database Consortium (IWWD) & Spanish Rectal Cancer Viking Consortium.
Risks of Organ Preservation in Rectal Cancer: Data From Two International Registries on Rectal Cancer
J Clin Oncol. 2025 May 10;43(14):1663-1672.
DOI: 10.1200/JCO.24.00405
IF: 42.1

Zaffaroni G, Mannucci A, Koskenvuo L, de Lacy B, Maffioli A, Bisseling T, Half E, Cavestro GM, Valle L, Ryan N, Aretz S, Brown K, Buttitta F, Carneiro F, Claber O, Blanco-Colino R, Collard M, Crosbie E, Cunha M, Doulias T, Fleming C, Heinrich H, Hüneburg R, Metras J, Nagtegaal I, Negoi I, Nielsen M, Pellino G, Ricciardiello L, Sagir A, Sánchez-Guillén L, Seppälä TT, Siersema P, Striebeck B, Sampson JR, Latchford A, Parc Y, Burn J, Möslein G.
Updated European guidelines for clinical management of familial adenomatous polyposis (FAP), MUTYH-associated polyposis (MAP), gastric adenocarcinoma, proximal polyposis of the stomach (GAPPS) and other rare adenomatous polyposis syndromes: a joint EHTG-ESCP revision.
Br J Surg. 2024 May 3;111(5):znae070
DOI: 10.1093/bjs/znae070
IF: 8.7

Perea J, García JL, Corchete LA, Martí M, Hernández-Villafranca S, Alcázar JA, Álvaro E, Hurtado E, Jiménez-Toscano M, Balaguer F, Ballestero A, López-Rojo I, Jiménez F, Sanz G, Melone S, Brandáriz L, Vivas A, Alvarellos A, González-Sarmiento R; Spanish Early-Onset Colorectal Cancer Consortium (SECOC).
Chromosomal breaks: another differential gap between early-onset and late-onset colorectal cancers.
Br J Surg. 2024 Mar 2;111(3):znae041
DOI: 10.1093/bjs/znae041
IF: 8.7

Dal Cero M, Gibert J, Grande L, Gimeno M, Osorio J, Bencivenga M, Fumagalli Romario U, Rosati R, Morgagni P, Gisbertz S, Polkowski WP, Lara Santos L, Kołodziejczyk P, Kielan W, Reddavid R, van Sandick JW, Baiocchi GL, Gockel I, Davies A, Wijnhoven BPL, Reim D, Costa P, Allum WH, Piessen G, Reynolds JV, Mönig SP, Schneider PM, Garsot E, Eizaguirre E, Miró M, Castro S, Miranda C, Monzonis-Hernández X, Pera M, On Behalf Of The Spanish Eurecca Esophagogastric Cancer Group And The European Gastrodata Study Group.
International External Validation of Risk Prediction Model of 90-Day Mortality after Gastrectomy for Cancer Using Machine Learning.
Cancers (Basel). 2024 Jul 5;16(13):2463
DOI: 10.3390/cancers16132463
IF: 4.5

Quiles MT, Rodríguez-Contreras A, Guillem-Marti J, Punset M, Sánchez-Soto M, López-Cano M, Sabadell J, Velasco J, Armengol M, Manero JM, Arbós MA.
Effect of Functionalization of Texturized Polypropylene Surface by Silanization and HBII-RGD Attachment on Response of Primary Abdominal and Vaginal Fibroblasts.
Polymers (Basel). 2024 Feb 29;16(5):667
DOI: 10.3390/polym16050667
IF: 4.7

Selected Projects

Profilaxis antibiótica oral + parenteral en cirugía colónica con preparación mecànica vs sin preparación mecánica: ensayo clínico prospectivo, randomizado, controlado y multicéntrico.
Principal Investigator: Eloi Espín Basany
Agency: Instituto de Salud Carlos III
Funding: 32,670 €
Period: 2021-2025

Impacto de la cirugía bariátrica en la hemodinámica portal en pacientes con obesidad mórbida y NAFLD. Estudio HEYMDAL.
Principal Investigator: Ramon Vilallonga Puy
Agency: Instituto de Salud Carlos III
Funding: 171,820 €
Period: 2023-2025

ENSAYO CLÍNCO EN FASE II PARA EVALUAR LA SEGURIDAD Y EFICACIA DEL TRATAMIENTO CON CELULAS TRONCALES ALOGENICAS MESENQUIMALES DERIVADAS DE LA GRASA EN PACIENTES CON ESTENOSIS INFLAMATORIA UNICA EN EL CONTEXTO DE LA ENFERMEDAD DE CROHN
Principal Investigator: Marc Martí Gallostra
Agency: Instituto de Salud Carlos III
Funding: 21,714 €
Period: 2023-2026

Incidence and clinical relevance of perioperative elevation of Troponin I and N- Terminal Pro- Brain natriuretic peptide in patients undergoing lung resection
Principal Investigator: Miriam de Nadal Clanchet
Agency: Instituto de Salud Carlos III
Funding: 119,185 €
Period: 2021-2025

ARTEMIs: AcceleRating the Translation of virtual twins towards a pErsonalised Management of fatty lIver patients
Principal Investigator: José Raul Herance Camacho
Agency: EUROPEAN COMMISSION
Funding: 724,000 €
Period: 2024-2027

VHIR Annual Report 2024