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Donation and transplantation of organs, tissues and cells

Publications
%Q1
Number of citations
% Open Access Publications
Ongoing Projects
Number of Presented Theses
Number of Active Clinical Trials
Throughout 2024, our group has continued advancing projects aimed at expanding the organ pool: 1) Concluded inclusion in a multicenter study on preoperative statin use and lung graft dysfunction (AES/ISCIII PI19/01660); 2) Continued enrollment in a study on mechanical insufflation-exsufflation (MI-E) in donor lung maintenance (AP176932021); 3) MPS-LOC (PLEC2022-009481): development of liver-on-chip systems using microfluidics, 3D printing, human liver cells, and bio-inks to replace animal testing; 4) 3DLiver (CPP2021-008633): creation of 3D liver models for ADMETox drug testing; 5) PRECOCE: novel corneal preservation with cerium oxide nanoparticles. New projects: 6) ECABOX: external eye preservation system for regenerative therapy and transplantation; 7) MTHiV: use of portal blood to accelerate liver maturation and assess effects on bioengineered hepatic tissue.

eCORE

  • Advanced Therapies and Advanced Interventions, Nanomedicine, Transplant & Donation
  • Chronic, Prevalent Diseases & Aging
  • Woman & Child Health & Rare Diseases

Team

Group Leader
Alberto Sandiumenge Camps

Principal Investigator (PI)
Alberto Sandiumenge Camps

Researchers
David Lorente García, Cristopher Alan Mazo Torre, Maria Déu Martin, Teresa Pont Castellana, Javier Jose Puig Galy, Elisabeth Navas Moya, Diana Colon Segade Rodriguez Martinez, Jose Ignacio Nuria Nieta, Nicolau Esteve Trias Adrhoe, Cristina Bernadó Morales, Anna Vilarrodona Serrat, M. Luisa Perez Rodriguez

PhD Students
Aroa Gomez Brey, Joaquim Fernandez Doblas

Nursing and Technical Staff
Anna Lucea Peña, Imma Garcia Ruiz, Carmen Valles Guerra, Irene Salvador Roses, Lis Vidal Valdivia, Sandra Torres Sierra, Tamara Gomez Lopez, Lidia Frias Jimenez, Anna Luque Jimenez, Pau Farres Frias, Carlos Martín Pérez, Anna Sole Fores, Jose Alejandro Marín Figuera, Vanesa Asenjo Gomez, Alan Muñoz Soler, Tomas Van Eeckhout Carter, Natzaret Pujagut Mercader, Raquel Bermudo Gascóm, Elba Agustí Rovira, Carlos Torrico Leon, Laura Lopez Puerto

Selected Publications

Bayes-Genis A, Gastelurrutia P, Monguio-Tortajada M, Camara ML, Prat-Vidal C, Cediel G, Rodriguez-Gomez L, Teis A, Revuelta-Lopez E, Ferrer-Curriu G, Roura S, Galvez-Monton C, Bisbal F, Vives J, Vilarrodona A, Munoz-Guijosa C, Querol S
Implantation of a double allogeneic human engineered tissue graft on damaged heart: insights from the PERISCOPE phase I clinical trial.
EBioMedicine
DOI: 10.1016/j.ebiom.2024.105060
IF: 9.70

Oliver-Gutierrez D, Gutuleac L, Anglada-Masferrer N, Segura-Duch G, Martin S, Bisbe L, Martin-Gomez MT, Zapata MA, Puig JJ
Therapeutic Keratoplasty for Fusarium Keratitis.
Journal of Clinical Medicine
DOI: 10.3390/jcm13247775
IF: 3.00

Perez-Blanco A, Acevedo M, Padilla M, Gomez A, Zapata L, Barber M, Martinez A, Calleja V, Rivero MC, Fernandez E, Velasco J, Flores EM, Quindos B, Rodriguez ST, Virgos B, Robles JC, Nebra AC, Moya J, Trenado J, Garcia N, Vallejo A, Herrero E, Garcia A, Rodriguez ML, Garcia F, Lara R, Lage L, Gil FJ, Guerrero FJ, Meilan A, Del Prado N, Fernandez C, Coll E, Dominguez-Gil B
Assessing Outcomes of Patients Subject to Intensive Care to Facilitate Organ Donation: A Spanish Multicenter Prospective Study.
TRANSPLANT INTERNATIONAL
DOI: 10.3389/ti.2024.12791
IF: 2.70

Sandiumenge A, Bello I, Coll-Torres E, Gomez-Brey A, Franco-Jarava C, Minambres E, Perez-Redondo M, Mosteiro F, Sanchez-Moreno L, Crowley S, Fieira E, Suberviola B, Mazo CA, Agusti A, Pont T
Systemic Inflammation Differences in Brain-vs. Circulatory-Dead Donors: Impact on Lung Transplant Recipients.
TRANSPLANT INTERNATIONAL
DOI: 10.3389/ti.2024.12512
IF: 2.70

Grando L, Boada M, Faner R, Gomez-Olles S, Ruiz V, Bohils M, Albiol J, Marrero R, Rosell L, Salinas I, Ruiz D, Ruiz A, Rodriguez-Villar C, Urena A, Paredes-Zapata D, Guirao A, Sanchez-Etayo G, Molins L, Quiroga N, Gomez-Brey A, Michavila X, Sandiumenge A, Agusti A, Ramos R, Bello I
The impact of the EVLP on the lung microbiome and its inflammatory reaction.
TRANSPLANT INTERNATIONAL
DOI: 10.3389/ti.2024.12979
IF: 2.70

Selected Projects

Liver-on-Chip Microphysiological Systems for Drug Discovery and Testing
Principal Investigator: Alberto Sandiumenge Camps
Agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 106,047.2 €
Period: 01/11/2022 - 31/10/2025

Respiratory Physiotherapy as a Tool to Increase the Number of Solid Organ Donors."
Principal Investigator: Alberto Sandiumenge Camps
Agency: Fundación Invest. Médica Mutua Madrileña
Funding: 40,000 €
Period: 01/09/2021 - 31/08/2024

The Effect of Preoperative Treatment with Statins in Both Donor and Recipient on the Incidence of Primary Graft Dysfunction.
Principal Investigator: Alberto Sandiumenge Camps
Agency: Instituto de Salud Carlos III
Funding: 62,920 €
Period: 01/01/2020 - 30/06/2024

Corneal preservation using novel mineral antioxidants (cerium oxide nanoparticles). PRE-CO-CE Project.
Principal Investigator: Anna Vilarodona
Agency: Fundación Invest. Médica Mutua Madrileña
Funding: 150,000 €
Period: 2024 to 2027

Develop an external preservation system to keep the functions of human eyes alive for regenerative therapy studies and, in the future, transplants."
Principal Investigator: Alberto Sandiumenge Camps
Agency: Horizon 2020
Funding: 150,000 €
Period: 2022 to 2025

VHIR Annual Report 2024