- Traumatic Brain Injury (TBI). In 2024, we completed patient enrollment for the serum biomarker project (BRAINI2), which aims to predict brain injury and poor outcomes in elderly patients and children with mild TBI. To help prevent and raise awareness about the impact of TBIs, we collaborated with the ESCOLAB program.
- Hydrocephalus and CSF Dynamics Disorders. Our most significant project in this area is the creation of a non-invasive intracranial pressure monitoring system (SafeICP project), which utilizes a transcutaneous scattered light optical system.
- Congenital malformations of the cranio-vertebral junction. We have collaborated on designing and publishing clinical guidelines and recommendations for the diagnosis and surgical treatment of Chiari malformations in both adults and pediatric populations.
eCORE
- Brain & Mind and Behaviour
Team
Group Leader
Ma Antonia Poca Pastor
Principal Investigator (PI)
M. Antònia Poca Pastor, Fuat Arikan Abelló, Miriam de Nadal Clanchet
Researchers
Juan Sahuquillo Barris, Darío Fabián Gándara Sabatini, Francisco Ramón Martínez-Ricarte, Marcelino Báguena Martínez, Marilyn Riveiro Vilaboa, Anna Rey Pérez, Jacinto Baena Caparrós, Francisca Munar Bauzà, Alejandro Ferré Masó, Dulce Moncho Rodríguez, Maria Sueiras Gil
PhD Students
Federica Maruccia, David Sánchez Ortiz, Marta Peris Sales, Aasma Sahuquillo Muxi
Lab Technicians
Noelia Montoya Clemente
Nursing and Technical Staff
Lourdes Expósito Mozas, Monica Tarradas Ustrell
Selected Publications
Poca MA, Lopez-Bermeo D, Moncho D, Ferre A, Sanchez-Montañez A, Mestres O, Galve S, Sahuquillo J
Surgical outcomes in Chiari 1 and Chiari 1.5 Malformation treated by Posterior Fossa Reconstruction: A Comprehensive analysis of 110 Pediatric cases and Literature Review
Journal of Clinical Medicine 2024 Jun 30;13(13):3852
DOI: 10.3390/jcm13133852
IF: 3.0
Tagliabue S, Kacprzak M, Rey-Perez A, Baena J, Riveiro M, Maruccia F, Fischer JB, Poca MA, Durduran T
How the heterogeneity of the severely injured brain affects hybrid diffuse optical signals: case examples and guidelines
Neurophotonics 2024 Oct;11(4):045005. Epub 2024 Oct 18
DOI: 10.1117/1.NPh.11.4.045005
IF: 4.8
Lorton F, Lagares A, de la Cruz J, Méjan O, Pavlov V, Sapin V, Poca MA, Lehner M, Biberthaler P, Chauviré-Drouard A, Gras-Le-Guen C, Scherdel P; BRAINI–2 paediatric Collaborative group; Collaborators
Performance of glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) biomarkers in predicting CT scan results and neurological outcomes in children with traumatic brain injury (BRAINI-2 paediatric study): protocol of a European prospective multicentre study
BMJ open 2024 May 15;14(5):e083531
DOI: 10.1136/bmjopen-2023-083531
IF: 2.4
Kempen B, Depreitere B, Piper I, Sahuquillo J, Mircea Iencean S, Krishnan Kanthimathinathan H, Zipfel J, Barzdina A, Pezzato S, Jones PA, Lo TMM
Visualization of the intracranial pressure and time burden in childhood brain trauma: What we have learnt one decade on with KidsBrainIT
Journal of Neurotrauma 2024 Jul;41(13-14):e1651-e1659. Epub 2024 Apr 1
DOI: 10.1089/neu.2023.0254
IF: 4.2
Iaccarino C, Chibbaro S, Sauvigny T, Timofeev I, Zaed I, Franchetti S, Mee H, Belli A, Buki A, De Bonis P, Demetriades AK, Depreitere B, Fountas K, Ganau M, Germanò A, Hutchinson P, Kolias A, Lindner D, Lippa L, Marklund N, McMahon C, Mielke D, Nasi D, Peul W, Poca MA, Pompucci A, Posti JP, Serban NL, Splavski B, Florian IS, Tasiou A, Zona G, Servadei F
Consensus-based recommendations for diagnosis and surgical management of cranioplasty and post-traumatic hydrocephalus from a European panel
Brain and spine 2024 Jan 26:4:102761. eCollection 2024
DOI: 10.1016/j.bas.2024.102761
IF: 1.9
Selected Projects
Safe, non-invasive photonics platform for bedside detection of intracranial hypertension and other abnormalities of the cerebrospinal fluid dynamics (SafeICP) (PLEC2022-009290)
Principal Investigator: Coordinator: Turgut Durduran (ICFO); PI VHIR: Maria Antonia Poca
Agency: Ministerio de Ciencia
Funding: 239,799.56 €
Period: 2023 - 2025
Impact of cerebellar cognitive-affective syndrome (Schmahmann syndrome) in patients with a Chiari type 1 malformation (PI22/01082)
Principal Investigator: Maria Antonia Poca
Agency: Instituto de Salud Carlos III
Funding: 99,220 €
Period: 2023 - 2025
Biomarkers to improve diagnosis and management of mild traumatic brain injury (BRAINI2) (220325)
Principal Investigator: Maria Antonia Poca
Agency: EIT Health
Funding: 248,666 €
Period: 2022 - 2024
Unitat de Recerca Neurotraumamologia i Neurocirurgia (2021 SGR 00810)
Principal Investigator: Maria Antonia Poca
Agency: Generalitat de Catalunya, AGAUR
Funding: 60,000 €
Period: 2021 - 2025
Incidence and clinical relevance of perioperative elevation of Troponin I and N- Terminal Pro- Brain natriuretic peptide in patients undergoing lung resection (PI20/00154)
Principal Investigator: Miriam de Nadal Clanchet
Agency: Instituto de Salud Carlos III
Funding: 119,185 €
Period: 2021 - 2025
Selected Dissemination Activities
Traffic accidents and head injuries. Causes and consequences. Experience the problem firsthand: Know the causes and talk to the patient. (ESCOLAB)
Place: Vall d'Hebron University Hospital
Date: 01/01/1970
Brief: This activity is part of "La Setmana del Cervell" (Brain Week), an event in which more than 30 countries participate and whose aim is to bring science to the people on the street. In our case, we offer a course for teenagers in which we talk to them and demonstrate the dangers of traffic accidents, the influence of alcohol and drug use and the consequences they can have for them and their families. We bring them closer to reality by visiting various services and sharing firsthand experiences with people who have suffered accidents and their consequences.
This course is highly in demand from schools, which is why we are holding this first edition in March and a second one in November.
Traffic accidents and head injuries. Causes and consequences. Experience the problem firsthand: Know the causes and talk to the patient. (ESCOLAB)
Place: Vall d'Hebron University Hospital
Date: 01/01/1970
Brief: This activity is part of "La Setmana del Cervell" (Brain Week), an event in which more than 30 countries participate and whose aim is to bring science to the people on the street. In our case, we offer a course for teenagers in which we talk to them and demonstrate the dangers of traffic accidents, the influence of alcohol and drug use and the consequences they can have for them and their families. We bring them closer to reality by visiting various services and sharing firsthand with people who have suffered accidents and their consequences.
This course is in high demand from schools, which is why this is the second edition in 2024.
MORE INFO
La Nit de la Recerca (Research Night) Micro talks
Place: Online
Date: 01/01/1970
Brief: Three members of our group and a student who has completed her final degree project with us have participated by recording videos of short talks on the topic of the research project they are working on to bring science to the average user.
Aasma Sahuquillo Muxi: Neuroanatomy of the cognitive cerebellum: https://www.youtube.com/watch?v=GA-1mGB9dCk
Elia Valls: Understanding Idiopathic Normal Pressure Hydrocephalus (iNPH): https://www.youtube.com/watch?v=C_nLcCl-hec&t=31s
Marta Peris: Impact of red blood cell rupture on blood transfusions: https://www.youtube.com/watch?v=Pz5INYRl9TE
Mar Rodríguez: Automation and use of AI in the biomedical environment, diagnosis and monitoring: https://www.youtube.com/watch?v=Iyh0yzzgamA
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La Nit de la Recerca (Research Night) Researchers go to school
Place: IES Caterina Albert
Date: 10/03/2024
Brief: As part of the European Research Night in Catalonia (la Nit de la Recerca), research staff not only took to the streets to explain their research to the population, but also entered schools and institutes throughout the territory to share it with children and young people under the slogan "Researchers go to school".
One of our researchers went to an Institute to explain the project BrainI2 in which we work on biomarkers to improve the diagnose and treatment of patients with mild traumàtic brain injuries (TBI) to find a quicker and non-invasive way to predict by a simple blood sample if those patients can have bad outcomes due of the injury.
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La Nit de la Recerca (Research Night) Speed Dating
Place: CosmoCaixa Museum of Science
Date: 01/01/1970
Brief: Speed Dating is a dynamic format that offers the opportunity to reach a large audience, as there is constant rotation. The researchers were seated, and the audience rotated, spending a few minutes with each other. The investigator introduced the project and the audience can ask questions during their time. One of our researchers participated in this activity.
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