- Projects from competitive concurrence (10)
- Non-competitive projects from Patients’ Advocacy Groups (Asdent and Hipofam) (2)
- Original manuscripts as principal authors or co-authors (25)
- Contributions to scientific meetings (posters and oral communications) (12)
- Awards (2)
- Clinical trials in rare kidney diseases (17)
- Observational prospective research studies (7)
- Rare Kidney Diseases Registries (11)
- Clinical guidelines-Recommendations as expert members (1)
- Members of the Paediatric Research Hub (HUVH)
- Members of the European Rare Kidney Diseases Network (ERKNet)
- Members of the European Rare Network on paediatric transplantation: TransplantChild
- Master theses (2)
eCORE
- Personalized Medicine, Innovative Diagnostics, Molecular Imaging & Digital Health
- Woman & Child Health & Rare Diseases
Team
Group Leader
Anna Meseguer Navarro
Principal Investigator (PI)
Gema Ariceta Iraola, Gerard Cantero Recasens, Cristina Martínez Martínez
Researchers
Mónica Durán Fernández, Alejandro Cruz Gual, Sara Chocron de Benzaquen, Gloria Mª Fraga Rodriguez, Mercedes López González, Hector Rios Duro
PhD Students
Julieta Torchia, Maud Injeyan, Andrea Casal Pardo, Arne Van Durne, Carla Castells Esteve, Aitana Zapico Alonso
Lab Technicians
Anna Gelpí López, Maria Clotet Di Iorio, Eva Esquinas De La Cueva, Consuelo Garcia Carmona, Ashley Desire Lino Rivera
Nursing and Technical Staff
José Ramon Jarrín Luengo
Selected Publications
Durán M, Ariceta G, Semidey ME, Castells-Esteve C, Casal-Pardo A, Lu B, Meseguer A, Cantero-Recasens G
Renal antiporter ClC-5 regulates collagen I/IV through the β-catenin pathway and lysosomal degradation
Life Sci Alliance. 2024 Apr 26;7(7):e202302444
DOI: 10.26508/lsa.202302444
IF: 3.3
Ariceta G, Santos F, López Muñiz A, Hermida A, Matoses ML, Ventura A, Martin-Moreno PL, González E, Acuña L, Giner E, Vara J
Switching from immediate- to extended-release cysteamine in patients with nephropathic cystinosis: from clinical trials to clinical practice
Clin Kidney J. 2024 Mar 6;17(4):sfae049
DOI: 10.1093/ckj/sfae049
IF: 3.9
Burballa C, Duran M, Martínez C, Ariceta G, Cantero-Recasens G, Meseguer A
Isolation and characterization of exosome-enriched urinary extracellular vesicles from Dent's disease type 1 Spanish patients
Nefrologia (Engl Ed). 2023 Dec;43 Suppl 2:77-84. Epub 2024 Jan 28
DOI: 10.1016/j.nefroe.2024.01.016
IF: 2.0
Levtchenko E, Ariceta G, Arguedas Flores O, Bichet DG, Bockenhauer D, Emma F, Hoorn EJ, Koster-Kamphuis L, Nijenhuis T, Trepiccione F, Vargas-Poussou R, Walsh SB, Knoers NVAM
International expert consensus statement on the diagnosis and management of congenital nephrogenic diabetes insipidus (arginine vasopressin resistance).
Nat Rev Nephrol. 2025 Feb;21(2):83-96. Epub 2024 Oct 22
DOI: 10.1038/s41581-024-00897-z
IF: 28.7
Schaefer F, Al-Dakkak I, Anokhina K, Cohen D, Greenbaum LA, Ariceta G
Registry Analysis of Patients Switching to Ravulizumab From Eculizumab.
Kidney Int Rep. 2024 Jun 20;9(9):2648-2656
DOI: 10.1016/j.ekir.2024.06.020
IF: 5.7
Selected Projects
Biomarkers, targets and therapeutic solutions to improve the care of patients affected by Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis (FHHNC).
Principal Investigator: Gema Ariceta
Agency: Instituto de Salud Carlos III, ISCIII
Funding: 202,070 €
Period: 2023-2025
Role of ClC-5 on renal fibrosis. Discovery of potential biomarkers and therapeutic targets for Dent’s Disease 1 progression
Principal Investigator: Gerard Cantero-Recasens
Agency: Instituto de Salud Carlos III, ISCIII
Funding: 123,420 €
Period: 2023-2025
Host-microbiota interactions and defective gut mucosal integrity triggering glomerular damage in idiopathic nephrotic syndrome
Principal Investigator: Cristina Martínez
Agency: Instituto de Salud Carlos III, ISCIII
Funding: 84,700 €
Period: 2022-2024
La variabilidad fenotípica en pacientes afectados de HFHNC como oportunidad para entender las bases fisiopatológicas de la enfermedad y para la búsqueda de soluciones terapéuticas
Principal Investigator: Anna Meseguer
Agency: Sociedad Española de Nefrología, SENEFRO
Funding: 24,000 €
Period: 2023-2025
Unravelling ClC-5 role on glycosylation and its link with proximal tubule functioning
Principal Investigator: Gerard Cantero-Recasens
Agency: Mizutani Foundation for Glycoscience (Japan)
Funding: 45,000 €
Period: 2023-2025
Patents
Nucleic acid constructs and vectors for podocyte specific expression
Priority Number: EP22382421.0
Priority Date: 02/05/2022
Applicants: 60% VHIR (UAB and ICREA), 40% Ninevah.
Selected Dissemination Activities
54th Congress of the Spanish Society of Nephrology
Place: Valencia (Spain)
Date: 10/08/2024
Brief: J. Torchia, a Ph.D. student of our group, presented the work entitled "Differential expression of urinary miRNAs in patients with Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis: its correlation with disease progression" (Oral communication).
56th Annual Meeting of the European Society for Paediatric Nephrology
Place: Valencia (Spain)
Date: 01/01/1970
Brief: J. Torchia presented as an oral communication the work "Patients with Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis with different disease progression have a differential expression profile of urinary miRNAs", being awarded with the best abstract prize.
The 48th FEBS Congress
Place: Milano (Italy)
Date: 01/01/1970
Brief: A researcher from our group (J. Torchia) presented a work on AI-predicted drugs as possible therapeutic solutions for Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis.
17th International meeting on Mucins in Health and Disease
Place: Gothenburg, Sweeden
Date: 01/01/1970
Brief: Dr. Gerard Cantero-Recasens presented the work entitled "ClC-5 modulates MUC1 trafficking to regulate renal epithelial cells differentiation".
47th National Congress of Pediatric Nephrology
Place: Bilbao (Spain)
Date: 01/01/1970
Brief: J. Torchia presented a work on the urinary miRNA profiles and their correlation with renal progression of Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis. She obtained the best oral communication award.
